The two-day event will begin with Steven Djuric, Vice President, Discovery Chemistry and Technology at Abbvie presenting his key note address. His presentation will explore the “Progress Towards a Contemporary Medicinal Chemistry Technology Toolkit”. Steven Djuric will cover:
• Reducing cycle times and costs whilst improving the probability of technical success in the Drug Discovery process
• Advances in the development and introduction of several new enabling chemistry technologies, including flow photochemistry
• Integrating synthesis, purification and bioassay platforms
• Developing heterocycle synthesis by using a high temperature chemistry flow reactor
On day two of the event Steve Rees, Vice President, Discovery Biology at Astrazeneca will give an overview of “Transforming Success through Innovation and Collaboration” in drug discovery.
• Application of the AstraZeneca 5R strategy for target selection
• Development of innovative capabilities for compound management and hit identification
• Transforming lead optimisation through the automation and miniaturisation of chemistry
• Developing a portfolio of diverse therapeutic modalities to enable any target to be prosecuted
• Innovative models of collaboration with pharma, vendor and academic partners
Joining Abbvie and Astrazeneca at SMi’s industry leading Drug Discovery conference are GSK, GHPC GmbH, Bayer AG, Medimmune, Epizyme, Vernalis, TissuSE GmbH and more!
Alongside the two-day conference, there will be two pre-conference workshops taking place on Tuesday 20th March 2018. The morning session will be led by Nicolas Clare, Technical Project Leader at Axol Bioscience. He will discuss Induced Pluripotent Stem Cell Derived Models and their use in Drug Discovery. The workshop is aimed at those who would like to understand the revolutionary biological technique of creating induced pluripotent stem cells (Ipsc) from any source material, differentiating them into different cell lineages and their use in drug discovery, either as healthy controls or disease models.
The afternoon workshop will be led by Emanuela Cuomo, Associate Principal Scientist at AstraZeneca who will provide an overview of CRISPR/Cas technologies and how they are applied to drug development. Specific examples will illustrate how genome editing is used in AstraZeneca pipeline to improve target identification and validation; also how it can be used to predict drug resistance and direct drug optimisation.
For more details about the conference and registration information, visit www.drug-discovery.co.uk/1888
21st – 22nd March 2018
Copthorne Tara Hotel, London, UK
For sponsorship and exhibition queries please contact Alia Malick at amalick ( @ ) smi-online dot co dot uk dot For delegate queries please contact Kieran Ronaldson at kronaldson ( @ ) smi-online dot co dot uk dot For media queries please contact Natasha Boumediene at nboumediene ( @ ) smi-online dot co dot uk dot
About SMi Group:
Established since 1993, the SMi Group is a global event-production company that specializes in Business-to-Business Conferences, Workshops, Masterclasses and online Communities. We create and deliver events in the Defence, Security, Energy, Utilities, Finance and Pharmaceutical industries. We pride ourselves on having access to the world’s most forward thinking opinion leaders and visionaries, allowing us to bring our communities together to Learn, Engage, Share and Network. More information can be found at http://www.smi-online.co.uk
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